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Neuerscheinung: "The Oxford Handbook of Evolutionary Medicine" (Eds. Martin Brüne & Wulf Schiefenhövel, 2019)



The Oxford Handbook of Evolutionary Medicine
Eds. Martin Brüne and Wulf Schiefenhövel

Medicine is grounded in the natural sciences, among which biology stands out with regard to the understanding of human physiology and conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system to find adequate responses.

In addition, many adaptations to past ecologies have turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. In addition, depression, anxiety and other psychiatric conditions add to the list.

The Oxford Handbook of Evolutionary Medicine is a compilation of cutting edge insights into the evolutionary history of ourselves as a species, and how and why our evolved design may convey vulnerability to disease. Written in a classic textbook style emphasising physiology and pathophysiology of all major organ systems, the Oxford Handbook of Evolutionary Medicine will be valuable for students as well as scholars in the fields of medicine, biology, anthropology and psychology.


Table of Contents
Part I: General Principles
1: Core Principles for Evolutionary Medicine, Randolph Nesse
2: Cellular Signalling Systems, Diana Le Duc & Torsten Schöneberg
3: Genetics and Epigenetics, Paul Ewald & Holly Swain Ewald
4: Growth and Development, Robin Miriam Bernstein & Barry Bogin
5: Senescence and Ageing, Xiaqing Zhao & Daniel Promislow
6: Nutrition, Body Composition, Physical Activity, and Energy Expenditure, Ann Caldwell, S. Boyd Eaton & Melvin Konner

Part II: Specific Systems
7: Musculoskeletal System, Martin Häusler, Nicole Bender, Lafi Aldakak, Francesco M. Galassi, Patrick Eppenberger, Maciej Henneberg & Frank Rühli
8: Skin and Integument, Mark Hill
9: Haematopoetic System, Eric Pietras & James DeGregori
10: Immune System, Graham Rook
11: Cardiovascular System, Kevin S. Shah, Kalyanam Shivkumar, Mehdi Nojo & Barbara Natterson-Horowitz
12: Respiratory System, Olga Carvalho & John Maina
13: Digestive System, John Furness, Eve K. Boyle, Josiane Fakhry, Joanna Gajewski & Linda J Fothergill
14: Excretory System, Paola Romagnani & Hans-Joachim Anders
15: Endocrinology, Richard Bribiescas
16: Sexuality, Reproduction, and Birth, Wulf Schiefenhövel & Wenda Trevathan
17: Brain, Spinal Cord and Sensory Systems, Martin Brüne
18: The Future of Medicine, Wulf Schiefenhövel & Martin Brüne

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